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Rad50 (DGR15331) Rabbit mAb
db11422
Datasheet
- Background The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010]
- Immunogen Recombinant protein of human Rad50
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Gene ID
10111
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Swiss Prot
Q92878
- Synonyms NBSLD; RAD502; hRad50
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P
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Recommended dilution
WB: 1:1000
IHC-P: 1:500-1:2000 - Calculated MW 154 kDa
- Observed MW 154 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR15331
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of Rad50 in Hela,A549,HL-60 using Rad50 antibody(1:1000 diluted) -
Immunohistochemical analysis of paraffin-embedded human Cholangiocarcinoma using db11422 antibody.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
