您当前的位置：
RUNX2 (DGR31289) Rabbit mAb
db11528
Datasheet
- Background This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2016]
- Immunogen A synthetic peptide of human RUNX2
-
Gene ID
860
12393
367218
-
Swiss Prot
Q13950
Q08775
Q9Z2J9
- Synonyms CCD; AML3; CCD1; CLCD; OSF2; CBFA1; OSF-2; PEA2aA; PEBP2aA; CBF-alpha-1
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, IP
-
Recommended dilution
WB: 1:1000
IHC-P: 1:200-1:2000
IP: 1:20-1:50 - Calculated MW 57 kDa
- Observed MW 55-62 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR31289
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
-
Western blot analysis of extracts from HeLa，A431 cells using db11528 at 1:1000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
