SF3B1单克隆抗体(DGR31370) | 高特异性&高亲和力

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Recombinant DGRmAb^®

SF3B1 (DGR31370) Rabbit mAb

db11801

Datasheet

Product Name : SF3B1 (DGR31370) Rabbit mAb

Cat.No.: db11801

Synonyms : MDS; PRP10; Hsh155; PRPF10; SAP155; SF3b155

Application : WB, IHC-P, ICC/IF, FC

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human SF3B1
Gene ID 23451
Swiss Prot O75533
Synonyms MDS; PRP10; Hsh155; PRPF10; SAP155; SF3b155
Reactivity Human,Mouse,Rat
Application WB, IHC-P, ICC/IF, FC
Recommended dilution WB: 1:1000-1:5000
IHC-P: 1:100-1:200
ICC/IF: 1:200-1:500
FC: 1:200-1:2000
Calculated MW 146 kDa
Observed MW 155 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR31370
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of SF3B1 in Hela,CHO-K1,C6,Ramos using SF3B1 antibody(1:1000 diluted)
Immunohistochemical analysis of paraffin-embedded human lung cancer using db11801 antibody.
Immunofluorescent analysis of 293T cells using db11801 antibody (green), and DAPI (blue).

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