您当前的位置：
RASGRF1 (DGR13600) Rabbit mAb
db11878
Datasheet
- Background The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]
- Immunogen A synthetic peptide of human RASGRF1
-
Gene ID
5923
-
Swiss Prot
Q13972
- Synonyms GNRP; GRF1; CDC25; GRF55; CDC25L; H-GRF55; PP13187; ras-GRF1
- Reactivity Human,Rat
- Application WB
- Recommended dilution WB: 1:1000-1:5000
- Calculated MW 145 kDa
- Observed MW 145 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR13600
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
-
Western blot detection of CDC25 in Rat Brain lysates using CDC25 antibody(1:1000 diluted).
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
