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MSH6 (DGR11978) Rabbit mAb
db11969
Datasheet
- Background This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]
- Immunogen A synthetic peptide of human MSH6
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Gene ID
2956
-
Swiss Prot
P52701
- Synonyms GTBP; HSAP; p160; GTMBP; HNPCC5
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, ICC/IF
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:200-1:500
ICC/IF: 1:200-1:500 - Calculated MW 163 kDa
- Observed MW 163 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR11978
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of MSH6 in K562,C6,3T3,Hela cell lysates using MSH6 antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded human tonsil using db11969 antibody. -
Immunofluorescent analysis of HeLa cells using db11969 antibody (green), and DAPI (blue).
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
