SET单克隆抗体(DGR18469) | 高特异性&高亲和力

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Recombinant DGRmAb^®

SET (DGR18469) Rabbit mAb

db12012

Datasheet

Product Name : SET (DGR18469) Rabbit mAb

Cat.No.: db12012

Synonyms : 2PP2A; IGAAD; TAF-I; I2PP2A; IPP2A2; PHAPII; TAF-IBETA

Application : WB, IHC-P, ICC/IF, FC, IP

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Immunogen A synthetic peptide of human SET
Gene ID 6418
Swiss Prot Q01105
Synonyms 2PP2A; IGAAD; TAF-I; I2PP2A; IPP2A2; PHAPII; TAF-IBETA
Reactivity Human,Mouse,Rat
Application WB, IHC-P, ICC/IF, FC, IP
Recommended dilution WB: 1:5000-1:50000
IHC-P: 1:100-1:200
ICC/IF: 1:500-1:1000
FC: 1:10-1:100
IP: 1:20-1:50
Calculated MW 34 kDa
Observed MW 39 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR18469
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of SET in K562,Hela cell lysates using SET antibody(1:1000 diluted).
Immunohistochemical analysis of paraffin-embedded human lung cancer using db12012 antibody.
Immunofluorescent analysis of HeLa cells using db12012 antibody (green), and DAPI (blue).

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