Phospho-Nucleophosmin (Thr95) (DGR33711) Rabbit mAb
Product Name :
Phospho-Nucleophosmin (Thr95) (DGR33711) Rabbit mAb
Cat.No.:
db12622
Synonyms :
B23; NPM
Application :
WB
Reactivity :
Human
Host species :
Rabbit
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Background
The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified. [provided by RefSeq, Aug 2017]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Thr95 of human Nucleophosmin
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Gene ID
4869
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Swiss Prot
P06748
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Synonyms
B23; NPM
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Reactivity
Human
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Application
WB
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Recommended dilution
WB: 1:1000-1:5000
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Calculated MW
33 kDa
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Observed MW
38 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR33711
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from HeLa cells using db12622 at 1:1000.
订购信息
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Package
Price (RMB)
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10μL
398
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.