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Phospho-EGFR (Tyr1086) (DGR31586) Rabbit mAb
db12702
Datasheet
- Background The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of coronavirus disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jun 2020]
- Immunogen A synthetic phosphopeptide corresponding to residues surrounding Tyr1086 of human EGFR
-
Gene ID
1956
-
Swiss Prot
P00533
- Synonyms ERBB; HER1; mENA; ERBB1; PIG61; NISBD2
- Reactivity Human
- Application WB, ICC/IF
-
Recommended dilution
WB: 1:1000-1:5000
ICC/IF: 1:100-1:200 - Calculated MW 134 kDa
- Observed MW 175 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR31586
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
