Slow Skeletal Myosin Heavy chain单克隆抗体(DGR20082) | 高特异性&高亲和力

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Recombinant DGRmAb^®

Slow Skeletal Myosin Heavy chain (DGR20082) Rabbit mAb

db12818

Datasheet

Product Name : Slow Skeletal Myosin Heavy chain (DGR20082) Rabbit mAb

Cat.No.: db12818

Synonyms : CMH1; MPD1; SPMD; SPMM; CMD1S; MYHCB

Application : IHC-P

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human Slow Skeletal Myosin Heavy chain
Gene ID 4625
Swiss Prot P12883
Synonyms CMH1; MPD1; SPMD; SPMM; CMD1S; MYHCB
Reactivity Human,Mouse,Rat
Application IHC-P
Recommended dilution IHC-P: 1:200-1:2000
Calculated MW 224 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR20082
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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