您当前的位置：
PD-L1 (DGR16014) Rabbit mAb
db12921
Datasheet
- Background This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
- Immunogen A synthetic peptide of human PD-L1
-
Gene ID
29126
-
Swiss Prot
Q9NZQ7
- Synonyms B7-H; B7H1; PDL1; PD-L1; hPD-L1; PDCD1L1; PDCD1LG1
- Reactivity Human
- Application WB, IHC-P, ICC/IF, FC, IP
-
Recommended dilution
WB: 1:1000
IHC-P: 1:200-1:500
ICC/IF: 1:100-1:200
FC: 1:100
IP: 1:20-1:50 - Calculated MW 33 kDa
- Observed MW 40-50 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR16014
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
×
![]()
-
Western blot analysis of extracts from HeLa cells using db12921 at 1:1000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
