Phospho-LAT (Tyr200) Rabbit pAb
Product Name :
Phospho-LAT (Tyr200) Rabbit pAb
Cat.No.:
db1296
Synonyms :
LAT1; pp36; IMD52
Application :
WB, ICC/IF
Reactivity :
Human
Host species :
Rabbit
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Background
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding
Tyr200 of human LAT
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Gene ID
27040
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Swiss Prot
O43561
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Synonyms
LAT1; pp36; IMD52
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Reactivity
Human
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Application
WB, ICC/IF
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Recommended dilution
WB: 1:2000
ICC/IF: 1:50
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Calculated MW
28 kDa
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Observed MW
36-38 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.