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Annexin VII (DGR11155) Rabbit mAb
db13227
Datasheet
- Background Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion. [provided by RefSeq, Jul 2008]
- Immunogen Recombinant protein of human Annexin VII
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Gene ID
310
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Swiss Prot
P20073
- Synonyms SNX; ANX7; SYNEXIN
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, IP
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:100-1:200
IP: 1:50 - Calculated MW 53 kDa
- Observed MW 51,47 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR11155
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of Annexin VII in K562,Rat Brain,Hela cell lysates using Annexin VII antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded human tonsil using db13227 antibody.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
