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PAR4 (DGR32963) Rabbit mAb
db13494
Datasheet
- Background This gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms. The intracellular mechanism involves the inhibition of pro-survival pathways and the activation of Fas-mediated apoptosis, while the extracellular mechanism involves the binding of a secreted form of this protein to glucose regulated protein 78 (GRP78) on the cell surface, which leads to activation of the extrinsic apoptotic pathway. This gene is located on the unstable human chromosomal 12q21 region and is often deleted or mutated different tumors. The encoded protein also plays an important role in the progression of age-related diseases. [provided by RefSeq, Aug 2017]
- Immunogen A synthetic peptide of human PAR4
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Gene ID
5074
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Swiss Prot
Q96IZ0
- Synonyms PAR4; Par-4
- Reactivity Human,Mouse
- Application WB, IP
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Recommended dilution
WB: 1:2000-1:20000
IP: 1:10-1:100 - Calculated MW 37 kDa
- Observed MW 41 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR32963
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of PAR4 in Hela,A549,HL-60,U251,U87-MG cell lysates using PAR4 antibody(1:1000 diluted).
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
