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SAFB (DGR19959) Rabbit mAb
db13550
Datasheet
- Background This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011]
- Immunogen A synthetic peptide of human SAFB
-
Gene ID
6294
-
Swiss Prot
Q15424
- Synonyms HAP; HET; SAF-B; SAFB1; SAB-B1; SAF-B1
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, ICC/IF
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:200-1:500
ICC/IF: 1:100 - Calculated MW 103 kDa
- Observed MW 150 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR19959
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of SAFB in K562,3T3,Hela cell lysates using SAFB antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using db13550 antibody. -
Immunofluorescent analysis of 293 cells using db13550 antibody (green), and DAPI (blue).
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
