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PML Protein (DGR31475) Rabbit mAb
db13765
Datasheet
- Background The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- Immunogen Recombinant protein of human PML Protein
-
Gene ID
5371
-
Swiss Prot
P29590
- Synonyms MYL; RNF71; PP8675; TRIM19
- Reactivity Human
- Application WB, IHC-P, ICC/IF, IP
-
Recommended dilution
WB: 1:1000
IHC-P: 1:200-1:2000
ICC/IF: 1:200-1:500
IP: 1:50-1:100 - Calculated MW 98 kDa
- Observed MW 48-130 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR31475
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from HeLa cells using db13765 at 1:1000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
