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Phospho-Rb (Thr826) (DGR13991) Rabbit mAb
db13996
Datasheet
- Background The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic phosphopeptide corresponding to residues surrounding Thr826 of human Rb
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Gene ID
5925
-
Swiss Prot
P06400
- Synonyms RB; pRb; OSRC; pp110; p105-Rb; PPP1R130
- Reactivity Human
- Application WB, IP
-
Recommended dilution
WB: 1:1000-1:5000
IP: 1:10-1:100 - Calculated MW 106 kDa
- Observed MW 106 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR13991
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
