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GTPBP4 (DGR32357) Rabbit mAb
db14033
Datasheet
- Background GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human GTPBP4/NOG1
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Gene ID
23560
-
Swiss Prot
Q9BZE4
- Synonyms NGB; CRFG; NOG1
- Reactivity Human
- Application WB, IHC-P
-
Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:200-1:500 - Calculated MW 74 kDa
- Observed MW 80 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR32357
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of GTPBP4/NOG1 in A549,HL-60 using GTPBP4/NOG1 antibody(1:1000 diluted) -
Immunohistochemical analysis of paraffin-embedded human tonsil using db14033 antibody.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
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For research use only. Not intended for diagnostic.
