SF3B3单克隆抗体(DGR13276) | 高特异性&高亲和力

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Recombinant DGRmAb^®

SF3B3 (DGR13276) Rabbit mAb

db14039

Datasheet

Product Name : SF3B3 (DGR13276) Rabbit mAb

Cat.No.: db14039

Synonyms : RSE1; SAP130; SF3b130; STAF130

Application : WB, IHC-P, ICC/IF, FC, IP

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human SF3B3
Gene ID 23450
Swiss Prot Q15393
Synonyms RSE1; SAP130; SF3b130; STAF130
Reactivity Human,Mouse,Rat
Application WB, IHC-P, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
IHC-P: 1:500-1:2000
ICC/IF: 1:200-1:500
FC: 1:100-1:200
IP: 1:50
Calculated MW 136 kDa
Observed MW 136 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR13276
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of SF3B3 in SHSY-5Y,C6 cell lysates using SF3B3 antibody(1:1000 diluted).
Immunofluorescent analysis of HeLa cells using db14039 antibody (green), and DAPI (blue).

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