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DPD (DGR19150) Rabbit mAb
db14649
Datasheet
- Background The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
- Immunogen A synthetic peptide of human DPD
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Gene ID
1806
-
Swiss Prot
Q12882
- Synonyms DHP; DPD; DHPDHASE
- Reactivity Human
- Application WB, IHC-P, ICC/IF, FC
-
Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:200-1:500
ICC/IF: 1:200-1:500
FC: 1:20-1:50 - Calculated MW 111 kDa
- Observed MW 111 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR19150
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of DPD in C6 cell lysates using DPD antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded human lung cancer using db14649 antibody. -
Immunofluorescent analysis of HeLa cells using db14649 antibody (green), and DAPI (blue). -
Western blot analysis of extracts from HeLa cells using db14649 at 1:1000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
