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Semaphorin 4D (DGR15010) Rabbit mAb
db14758
Datasheet
- Background Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.
- Immunogen A synthetic peptide of human Semaphorin 4D
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Gene ID
10507
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Swiss Prot
Q92854
- Synonyms CD100; COLL4; SEMAJ; coll-4; C9orf164; M-sema-G
- Reactivity Human
- Application WB, IHC-P, ICC/IF
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:100-1:200
ICC/IF: 1:100-1:200 - Calculated MW 96 kDa
- Observed MW 120 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR15010
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of Semaphorin 4D/CD100 in Jurkat cell lysates using Semaphorin 4D/CD100 antibody(1:500 diluted). -
Immunofluorescent analysis of Jurkat cells using db14758 antibody (green), and DAPI (blue).
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
