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SESN1 (DGR15876) Rabbit mAb
db14972
Datasheet
- Background This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
- Immunogen A synthetic peptide of human SESN1
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Gene ID
27244
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Swiss Prot
Q9Y6P5
- Synonyms PA26; SEST1
- Reactivity Human,Mouse,Rat
- Application WB, FC
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Recommended dilution
WB: 1:1000-1:5000
FC: 1:100-1:500 - Calculated MW 57 kDa
- Observed MW 70 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR15876
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from HeLa,K562 cells using db14972 at 1:1000. -
Western blot analysis of extracts from HepG2，HCT116，SW620 cells using db14972 at 1:3000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
