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Recombinant DGRmAb®
ALKBH5 (DGR15586) Rabbit mAb
Alternate Text
db15035
Datasheet

Product Name : ALKBH5 (DGR15586) Rabbit mAb

Cat.No.: db15035

Synonyms : ABH5; OFOXD; OFOXD1

Application : WB, IHC-P

Reactivity : Human,Mouse,Rat

Host species : Rabbit

  • Background Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N6-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Can also demethylate N6-methyladenosine in single-stranded DNA (in vitro) (PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron (PubMed:21264265, PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export (PubMed:23177736). Required for spermatogenesis (By similarity).
  • Immunogen Recombinant protein of human ALKBH5
  • Gene ID 54890
  • Swiss Prot Q6P6C2
  • Synonyms ABH5; OFOXD; OFOXD1
  • Reactivity Human,Mouse,Rat
  • Application WB, IHC-P
  • Recommended dilution WB: 1:1000
    IHC-P: 1:200-1:2000
  • Calculated MW 44 kDa
  • Observed MW 44-48 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR15586
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot analysis of extracts from HeLa cells using db15035 at 1:1000.
  • Western blot analysis of extracts from HepG2，C2C12，PC-12 cells using db15035 at 1:1000.
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期：现货
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For research use only. Not intended for diagnostic.