Asialoglycoprotein Receptor 2 (DGR15340) Rabbit mAb - diagbio

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Recombinant DGRmAb^®

Asialoglycoprotein Receptor 2 (DGR15340) Rabbit mAb

db15087

Datasheet

Product Name : Asialoglycoprotein Receptor 2 (DGR15340) Rabbit mAb

Cat.No.: db15087

Synonyms : HL-2; HBXBP; ASGPR2; ASGP-R2; CLEC4H2

Application : WB, IHC-P, IP

Reactivity : Human

Host species : Rabbit

Background This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Immunogen A synthetic peptide of human Asialoglycoprotein Receptor 2
Gene ID 433
Swiss Prot P07307
Synonyms HL-2; HBXBP; ASGPR2; ASGP-R2; CLEC4H2
Reactivity Human
Application WB, IHC-P, IP
Recommended dilution WB: 1:1000
IHC-P: 1:200-1:500
IP: 1:50-1:100
Calculated MW 35 kDa
Observed MW 45 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR15340
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot analysis of extracts from Human plasma tissue using db15087 at 1:1000.

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