您当前的位置：
Bag3 (DGR13167) Rabbit mAb
db15638
Datasheet
- Background BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human Bag3
-
Gene ID
9531
-
Swiss Prot
O95817
- Synonyms BIS; MFM6; BAG-3; CAIR-1
- Reactivity Human,Mouse
- Application WB, IP
-
Recommended dilution
WB: 1:1000-1:5000
IP: 1:10-1:100 - Calculated MW 62 kDa
- Observed MW 74-80 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR13167
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
-
Western blot analysis of extracts from HeLa cells using db15638 at 1:1000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
