RAMP1 Rabbit pAb - diagbio | 戴格生物

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RAMP1 Rabbit pAb

db1580

Datasheet

Product Name : RAMP1 Rabbit pAb

Cat.No.: db1580

Synonyms : Calcitonin-receptor-like receptor activity-modifying protein 1

Application : WB, FC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Immunogen A synthetic peptide of human RAMP1
Gene ID 10267
Swiss Prot O60894
Synonyms Calcitonin-receptor-like receptor activity-modifying protein 1
Reactivity Human, Mouse, Rat
Application WB, FC
Recommended dilution WB: 1:1000-1:5000
FC: 1:100
Calculated MW 17 kDa
Observed MW 17 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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