SDHB单克隆抗体(DGR11974) | 高特异性&高亲和力

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Recombinant DGRmAb^®

SDHB (DGR11974) Rabbit mAb

db15866

Datasheet

Product Name : SDHB (DGR11974) Rabbit mAb

Cat.No.: db15866

Synonyms : IP; SDH; CWS2; PGL4; SDH1; SDH2; SDHIP

Application : WB, IHC-P, FC, IP

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human SDHB
Gene ID 6390
Swiss Prot P21912
Synonyms IP; SDH; CWS2; PGL4; SDH1; SDH2; SDHIP
Reactivity Human,Mouse,Rat
Application WB, IHC-P, FC, IP
Recommended dilution WB: 1:5000-1:50000
IHC-P: 1:200-1:2000
FC: 1:20-1:200
IP: 1:10-1:100
Calculated MW 32 kDa
Observed MW 32 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR11974
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot analysis of extracts from HepG2，A431，Jurkat cells using db15866 at 1:1000.

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