Phospho-Filamin A (Ser1083) Rabbit pAb - diagbio | 戴格生物

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Phospho-Filamin A (Ser1083) Rabbit pAb

db1940

Datasheet

Product Name : Phospho-Filamin A (Ser1083) Rabbit pAb

Cat.No.: db1940

Synonyms : FLN; FMD; MNS; OPD; ABPX; CSBS; CVD1; FLN1; NHBP; OPD1; OPD2; XLVD; XMVD; FLN-A; ABP-280

Application : WB, ICC/IF, FC

Reactivity : Human

Host species : Rabbit

Background The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser1083 of human Filamin A
Gene ID 2316
Swiss Prot P21333
Synonyms FLN; FMD; MNS; OPD; ABPX; CSBS; CVD1; FLN1; NHBP; OPD1; OPD2; XLVD; XMVD; FLN-A; ABP-280
Reactivity Human
Application WB, ICC/IF, FC
Recommended dilution WB: 1:1000
ICC/IF: 1:50
FC: 1:20
Calculated MW 281 kDa
Observed MW 281 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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