Tissue Factor Pathway Inhibitor Rabbit pAb - diagbio | 戴格生物

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Tissue Factor Pathway Inhibitor Rabbit pAb

db21504

Datasheet

Product Name : Tissue Factor Pathway Inhibitor Rabbit pAb

Cat.No.: db21504

Synonyms : EPI; TFI; LACI; TFPI1

Application : WB

Reactivity : Human

Host species : Rabbit

Background This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016]
Immunogen A synthetic peptide of human TFPI
Gene ID 7035
Swiss Prot P10646
Synonyms EPI; TFI; LACI; TFPI1
Reactivity Human
Application WB
Recommended dilution WB: 1:1000
Calculated MW 35 kDa
Observed MW 40-55 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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