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Cyclin T1 Rabbit pAb
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Product Name : Cyclin T1 Rabbit pAb

Cat.No.: db5223

Synonyms : CCNT; CYCT1; HIVE1

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

  • Background This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
  • Immunogen Recombinant protein of human Cyclin T1
  • Gene ID 904
  • Swiss Prot O60563
  • Synonyms CCNT; CYCT1; HIVE1
  • Reactivity Human, Mouse, Rat
  • Application WB, IHC, ICC/IF, FC, IP
  • Recommended dilution WB: 1:1000
    IHC: 1:100
    ICC/IF: 1:100
    FC: 1:20
    IP: 1:20
  • Calculated MW 81 kDa
  • Observed MW 81 kDa
  • Host species Rabbit
  • Clonality Polyclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 598
  • 50μL 998
  • 100μL 1798
  • 货期:现货
For research use only. Not intended for diagnostic.