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FKBP12 Rabbit pAb
db5443
Datasheet
- Background The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq, Sep 2008]
- Immunogen A synthetic peptide of human FKBP12
-
Gene ID
2280
-
Swiss Prot
P62942
- Synonyms FKBP1; PKC12; PKCI2; FKBP12; PPIASE; FKBP-12; FKBP-1A
- Reactivity Human, Mouse, Rat
- Application WB, ICC/IF
-
Recommended dilution
WB: 1:2000-1:10000
ICC/IF: 1:20 - Calculated MW 12 kDa
- Observed MW 12 kDa
- Host species Rabbit
- Clonality Polyclonal
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
- Package Price (RMB)
- 20μL 598
- 50μL 998
- 100μL 1798
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
