Phospho-RNA polymerase II CTD repeat YSPTSPS (Ser5) Rabbit pAb - diagbio

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Phospho-RNA polymerase II CTD repeat YSPTSPS (Ser5) Rabbit pAb

db5524

Datasheet

Product Name : Phospho-RNA polymerase II CTD repeat YSPTSPS (Ser5) Rabbit pAb

Cat.No.: db5524

Synonyms : RPB1; RPO2; POLR2; POLRA; RPBh1; RPOL2; RpIILS; hsRPB1; hRPB220

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser5 of human RNA polymerase II CTD repeat YSPTSPS
Gene ID 5430
Swiss Prot P24928
Synonyms RPB1; RPO2; POLR2; POLRA; RPBh1; RPOL2; RpIILS; hsRPB1; hRPB220
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
IHC: 1:50
ICC/IF: 1:50
FC: 1:20
IP: 1:20
Calculated MW 192 kDa
Observed MW 250 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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