Product Name : Recombinant Human IL1R2 / CD121b Protein (Fc tag)
Cat.No.: db58314
Synonyms : CD121b;CDw121b;IL-1R-2;IL-1RT-2;IL-1RT2;IL1R2c;IL1RB
Tag : C-Fc
Expression host : HEK293 Cells
Species : Human
- Background Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
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Gene ID
7850
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Swiss Prot
P27930
- Synonyms CD121b;CDw121b;IL-1R-2;IL-1RT-2;IL-1RT2;IL1R2c;IL1RB
- Application Positive Control, Immunogen, SDS-PAGE, WB
- Molecular Weight 64.5 kDa
- Species Human
- Expression Host HEK293 Cells
- Purity >90% as determined by SDS-PAGE.
- Seq Met 1-Glu 343
- Tag C-Fc
- Formulation Freeze-dried powder
- Storage/Stability Store at 2-8℃ for one month. Aliquot and store at -80℃ for 12 months. Avoid repeated freeze/thaw cycles.
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15% SDS PAGE(reduced) analysis of Recombinant Human IL1R2 / CD121b Protein (Fc tag)
- Package Price (RMB)
- 10μg 860
- 50μg 1560
- 100μg 2560
- 1mg 14600
- 货期：现货
