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E2F1 (4G8) Mouse mAb
db6248
Datasheet

Product Name : E2F1 (4G8) Mouse mAb

Cat.No.: db6248

Synonyms : RBP3; E2F-1; RBAP1; RBBP3

Application : WB, ICC/IF, IP

Reactivity : Human, Mouse, Rat

Host species : Mouse

  • Background Transcription activator that binds DNA cooperatively with dp proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-1 binds preferentially RB1 protein, in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent apoptosis.
  • Immunogen Purified recombinant human E2F-1 protein fragments expressed in E.coli
  • Gene ID 1869
  • Swiss Prot Q01094
  • Synonyms RBP3; E2F-1; RBAP1; RBBP3
  • Reactivity Human, Mouse, Rat
  • Application WB, ICC/IF, IP
  • Recommended dilution WB: 1:500-1:1000
    ICC/IF: 1:50-1:200
    IP: 1:20
  • Calculated MW 47 kDa
  • Observed MW 70 kDa
  • Host species Mouse
  • Clonality Monoclonal
  • Clonality No. 4G8-2C2-C12
  • Isotype IgG2b
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in PBS, 50% Glycerol(pH 7.3), 0.02% sodium azide and 0.5% BSA . Stable for 12 months from date of receipt.
  • Western blot analysis of E2F1 in C6, Raw264.7 and Hela lysates using E2F1 antibody.
  • Immunofluorescence analysis of E2F1 (4G8) in Hela using E2F1 antibody,and DAPI (blue).
  • Immunoprecipitation analysis of E2F1 (4G8) in Hela lysates using E2F1 antibody.
订购信息
  • Package Price (RMB)
  • 50μL 1398
  • 100μL 2398
  • 货期：现货
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For research use only. Not intended for diagnostic.