XRCC4 (7C10) Mouse mAb - diagbio | 戴格生物

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XRCC4 (7C10) Mouse mAb

db6445

Datasheet

Product Name : XRCC4 (7C10) Mouse mAb

Cat.No.: db6445

Synonyms : X ray repair cross complementing protein 4; DNA repair protein XRCC4; DNA double strand break repair

Application : WB, IHC-P, ICC/IF, IP

Reactivity : Human, Mouse, Rat

Host species : Mouse

Background Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Immunogen Synthetic Peptide of XRCC4
Gene ID 7518
Swiss Prot Q13426
Synonyms X ray repair cross complementing protein 4; DNA repair protein XRCC4; DNA double strand break repair
Reactivity Human, Mouse, Rat
Application WB, IHC-P, ICC/IF, IP
Recommended dilution WB: 1:500-1:1000
IHC: 1:50-1:100
ICC/IF: 1:50-1:200
IP: 1:20
Calculated MW 38 kDa
Observed MW 38-45 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. 7C10-5H8-4F8
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% Glycerol(pH 7.3), 0.02% sodium azide and 0.5% BSA . Stable for 12 months from date of receipt.

Immunohistochemistry analysis of paraffin-embedded XRCC4 in Human lung cancer using XRCC4 (7C10) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Western blot analysis of XRCC4 (7C10) in XRCC4 in T47D, 3T3, COS7, C6 and Hela lysates using XRCC4 (7C10) antibody
Immunoprecipitation analysis of XRCC4 in Hela lysates using XRCC4 antibody.

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