Phospho-VASP (Ser239) Rabbit pAb - diagbio | 戴格生物

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Phospho-VASP (Ser239) Rabbit pAb

db7044

Datasheet

Product Name : Phospho-VASP (Ser239) Rabbit pAb

Cat.No.: db7044

Application : WB, IP

Reactivity : Human

Host species : Rabbit

Background Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser239 of human VASP
Gene ID 7408
Swiss Prot P50552
Reactivity Human
Application WB, IP
Recommended dilution WB: 1:1000
IP: 1:20
Calculated MW 40 kDa
Observed MW 48 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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