SMAC Recombinant Rabbit mAb - diagbio | 戴格生物

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SMAC Recombinant Rabbit mAb

db11117

Product Name : SMAC Recombinant Rabbit mAb

Cat.No.: db11117

Synonyms : SMAC; DFNA64

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Immunogen A synthetic peptide of human Smac/Diablo
Gene ID 56616
Swiss Prot Q9NR28
Synonyms SMAC; DFNA64
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
IHC: 1:20-1:100
ICC/IF: 1:100
FC: 1:20
IP: 1:20-1:50
Calculated MW 27 kDa
Observed MW 21 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Smac/Diablo in K562,Hela cell lysates using Smac/Diablo antibody(1:1000 diluted).

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