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ROCK1 Recombinant Rabbit mAb
db11120
Datasheet

Product Name : ROCK1 Recombinant Rabbit mAb

Cat.No.: db11120

Synonyms : ROCK-I; P160ROCK

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

  • Background This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18. [provided by RefSeq, Aug 2015]
  • Immunogen A synthetic peptide of human ROCK1
  • Gene ID 6093
  • Swiss Prot Q13464
  • Synonyms ROCK-I; P160ROCK
  • Reactivity Human, Mouse, Rat
  • Application WB, IHC, ICC/IF, FC, IP
  • Recommended dilution WB: 1:1000
    IHC: 1:50
    ICC/IF: 1:50
    FC: 1:100
    IP: 1:20
  • Calculated MW 158 kDa
  • Observed MW 158 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot detection of ROCK1 in K562,C6 cell lysates using ROCK1 antibody (1:1000 diluted).
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.