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AMPK alpha 2 Recombinant Rabbit mAb
db11167
Datasheet

Product Name : AMPK alpha 2 Recombinant Rabbit mAb

Cat.No.: db11167

Synonyms : AMPK; AMPK2; PRKAA; AMPKa2

Application : WB, IP

Reactivity : Human

Host species : Rabbit

  • Background The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]
  • Immunogen Recombinant protein of human AMPK alpha 2
  • Gene ID 5563
  • Swiss Prot P54646
  • Synonyms AMPK; AMPK2; PRKAA; AMPKa2
  • Reactivity Human
  • Application WB, IP
  • Recommended dilution WB: 1:1000
    IP: 1:20
  • Calculated MW 62 kDa
  • Observed MW 62 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot detection of AMPK alpha 2 in C6,Hela cell lysates using AMPK alpha 2 antibody(1:1000 diluted).
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.