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AMPK alpha 2 (DGR14497) Rabbit mAb (PBS Only)
db11167-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]
- Immunogen Recombinant protein of human AMPK alpha 2
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Gene ID
5563
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Swiss Prot
P54646
- Synonyms AMPK; AMPK2; PRKAA; AMPKa2
- Reactivity Human
- Application WB, IP
- Calculated MW 62 kDa
- Observed MW 62 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR14497
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot detection of AMPK alpha 2 in C6,Hela cell lysates using AMPK alpha 2 antibody(1:1000 diluted).
订购信息
- Package Price (RMB)
- 10μg 1898
- 100μg 5798
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
