CaMKII (DGR14655) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

CaMKII (DGR14655) Rabbit mAb

db11726

Datasheet

Product Name : CaMKII (DGR14655) Rabbit mAb

Cat.No.: db11726

Synonyms : CAMKA

Application : WB, IHC, ICC/IF, FC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]
Immunogen A synthetic peptide of human CaMKII
Gene ID 815
Swiss Prot Q9UQM7
Synonyms CAMKA
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC
Recommended dilution WB: 1:1000-1:2000
IHC: 1:200-1:500
ICC/IF: 1:20-1:100
FC: 1:20-1:100
Calculated MW 54 kDa
Observed MW 54 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR14655
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of CaMKII alpha in Rat Brain,Hela cell lysates using CaMKII alpha antibody(1:1000 diluted).
Western blot analysis of extracts from HepG2 cells using db11726 at 1:2000.

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