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ICAD Recombinant Rabbit mAb
db13280
Datasheet

Product Name : ICAD Recombinant Rabbit mAb

Cat.No.: db13280

Synonyms : DFF1; ICAD; DFF-45

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human

Host species : Rabbit

  • Background Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Immunogen A synthetic peptide of human ICAD
  • Gene ID 1676
  • Swiss Prot O00273
  • Synonyms DFF1; ICAD; DFF-45
  • Reactivity Human
  • Application WB, IHC, ICC/IF, FC, IP
  • Recommended dilution WB: 1:1000
    IHC: 1:100-1:500
    ICC/IF: 1:100
    FC: 1:20
    IP: 1:20
  • Calculated MW 37 kDa
  • Observed MW 45 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.