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Bcl-XL Recombinant Rabbit mAb
db14392
Datasheet

Product Name : Bcl-XL Recombinant Rabbit mAb

Cat.No.: db14392

Synonyms : BCLX; BCL2L; Bcl-X; PPP1R52; BCL-XL/S

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

  • Background The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. [provided by RefSeq, Dec 2015]
  • Immunogen Recombinant protein of human Bcl-XL
  • Gene ID 598
  • Swiss Prot Q07817
  • Synonyms BCLX; BCL2L; Bcl-X; PPP1R52; BCL-XL/S
  • Reactivity Human, Mouse, Rat
  • Application WB, IHC, ICC/IF, FC, IP
  • Recommended dilution WB: 1:5000
    IHC: 1:200
    ICC/IF: 1:200
    FC: 1:20
    IP: 1:20
  • Calculated MW 26 kDa
  • Observed MW 30 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot detection of Bcl-XL in Rat Brain,C6,3T3,Hela cell lysates using Bcl-XL antibody(1:1000 diluted).
  • Western blot detection of Bcl-XL in K562,Rat Brain,3T3 cell lysates using Bcl-XL antibody(1:1000 diluted).
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.