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Bcl-XL (DGR31954) Rabbit mAb (PBS Only)
db14392-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. [provided by RefSeq, Dec 2015]
- Immunogen Recombinant protein of human Bcl-XL
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Gene ID
598
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Swiss Prot
Q07817
- Synonyms BCLX; BCL2L; Bcl-X; PPP1R52; BCL-XL/S
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, IP
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Recommended dilution
WB: 1:2000-1:20000
IHC-P: 1:200-1:2000
IP: 1:50-1:100 - Calculated MW 26 kDa
- Observed MW 30 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR31954
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot detection of Bcl-XL in Rat Brain,C6,3T3,Hela cell lysates using Bcl-XL antibody(1:1000 diluted). -
Western blot detection of Bcl-XL in K562,Rat Brain,3T3 cell lysates using Bcl-XL antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded human colon cancer using db14392
订购信息
- Package Price (RMB)
- 100μg 4498
- 货期：现货
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For research use only. Not intended for diagnostic.
