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APAF1 Recombinant Rabbit mAb
db14482
Datasheet

Product Name : APAF1 Recombinant Rabbit mAb

Cat.No.: db14482

Synonyms : CED4; APAF-1

Application : WB, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

  • Background This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Immunogen Recombinant protein of human APAF1
  • Gene ID 317
  • Swiss Prot O14727
  • Synonyms CED4; APAF-1
  • Reactivity Human, Mouse, Rat
  • Application WB, IP
  • Recommended dilution WB: 1:1000
    IP: 1:20
  • Calculated MW 142 kDa
  • Observed MW 142 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.