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APAF1 (DGR19632) Rabbit mAb (PBS Only)
db14482-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Immunogen Recombinant protein of human APAF1
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Gene ID
317
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Swiss Prot
O14727
- Synonyms CED4; APAF-1
- Reactivity Human,Mouse,Rat
- Application WB, IP
- Calculated MW 142 kDa
- Observed MW 142 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR19632
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from 293 cells using db14482 at 1:1000.
订购信息
- Package Price (RMB)
- 100μg 5798
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
