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FAK (3D8) Mouse mAb

Product Name : FAK (3D8) Mouse mAb

Cat.No.: db6186

Synonyms : FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK

Application : WB, ICC/IF, IP

Reactivity : Human

Host species : Mouse

  • Background Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
  • Immunogen Purified recombinant human FAK protein fragments expressed in E.coli
  • Gene ID 5747
  • Swiss Prot Q05397
  • Synonyms FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK
  • Reactivity Human
  • Application WB, ICC/IF, IP
  • Recommended dilution WB: 1:500-1:1000
    ICC/IF: 1:50-1:200
    IP: 1:20
  • Calculated MW 119 kDa
  • Observed MW 125 kDa
  • Host species Mouse
  • Clonality Monoclonal
  • Clonality No. 3D8-H11-E12
  • Isotype IgG1
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.
  • Western blot analysis of FAK in COS7, HUVEC, A549 and Hela lysates using FAK antibody.
  • Immunofluorescence analysis of FAK (3D8) in Hela using FAK antibody.
  • Immunoprecipitation analysis of FAK (3D8) in Hela lysates using FAK antibody.
订购信息
  • Package Price (RMB)
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.