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FAK (3D8) Mouse mAb (PBS Only)
db6186-PBS
Datasheet

Product Name : FAK (3D8) Mouse mAb (PBS Only)

Cat.No.: db6186-PBS

Synonyms : FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK

Application：

Reactivity : Human

Host species : Mouse

Conjugation/Formulation：PBS Only

Un-conjugated PBS Only
  • Background Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
  • Immunogen Purified recombinant human FAK protein fragments expressed in E.coli
  • Gene ID 5747
  • Swiss Prot Q05397
  • Synonyms FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK
  • Reactivity Human
  • Application WB, ICC/IF, IP
  • Calculated MW 119 kDa
  • Observed MW 125 kDa
  • Host species Mouse
  • Clonality Monoclonal
  • Clonality No. 3D8-H11-E12
  • Isotype IgG1
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/mL
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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  • Western blot analysis of FAK in COS7, HUVEC, A549 and Hela lysates using FAK antibody.
  • Immunofluorescence analysis of FAK (3D8) in Hela using FAK antibody.
  • Immunoprecipitation analysis of FAK (3D8) in Hela lysates using FAK antibody.
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  • Package Price (RMB)
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  • 货期：现货
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For research use only. Not intended for diagnostic.