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beta Catenin (DGR13940) Rabbit mAb (PBS Only)
db11055-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
- Immunogen A synthetic peptide of human beta Catenin
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Gene ID
1499
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Swiss Prot
P35222
- Synonyms EVR7; CTNNB; MRD19; armadillo
- Reactivity Human,Mouse,Rat
- Application WB, ICC/IF, FC
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Recommended dilution
WB: 1:1000
ICC/IF: 1:100-1:200
FC: 1:20 - Calculated MW 86 kDa
- Observed MW 86 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR13940
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot detection of beta Catenin in C6 cell lysates using beta Catenin antibody(1:1000 diluted). -
Western blot analysis of extracts from HeLa cells using db11055 at 1:1000. -
Immunofluorescent analysis of 293T cells using db11055 antibody (green), and DAPI (blue).
订购信息
- Package Price (RMB)
- 100μg 5798
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
