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Recombinant DGRmAb®
Phospho-MCM2 (Ser108) (DGR13388) Rabbit mAb (PBS Only)
db11069-PBS
Datasheet

Product Name : Phospho-MCM2 (Ser108) (DGR13388) Rabbit mAb (PBS Only)

Cat.No.: db11069-PBS

Synonyms : BM28; CCNL1; CDCL1; cdc19; DFNA70; D3S3194; MITOTIN

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Conjugation/Formulation：PBS Only

Un-conjugated PBS Only
  • Background The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
  • Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser108 of human MCM2
  • Gene ID 4171
  • Swiss Prot P49736
  • Synonyms BM28; CCNL1; CDCL1; cdc19; DFNA70; D3S3194; MITOTIN
  • Reactivity Human, Mouse, Rat
  • Application WB, ICC/IF, IP
  • Recommended dilution WB: 1:1000
    ICC/IF: 1:50
    IP: 1:20
  • Calculated MW 102 kDa
  • Observed MW 125 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR13388
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/ml
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
  • Western blot analysis of extracts from K562, 3T3, HeLa cells using db11069 at 1:1000.
  • Western blot analysis of extracts from HepG2 cells using db11069 at 1:1000.
  • Immunofluorescent analysis of HeLa cells using db11069 antibody (green), and DAPI (blue).
  • Western blot analysis of extracts from Rat spleen tissue using db11069 at 1:1000.
订购信息
  • Package Price (RMB)
  • 100μg 4498
  • 货期：现货
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For research use only. Not intended for diagnostic.