GAD67单克隆抗体(DGR12432) | 高特异性&高亲和力

产品中心 Products Center

您当前的位置：

Recombinant DGRmAb^®

GAD67 (DGR12432) Rabbit mAb (PBS Only)

db11089-PBS

Datasheet

Product Name : GAD67 (DGR12432) Rabbit mAb (PBS Only)

Cat.No.: db11089-PBS

Synonyms : GAD; SCP; CPSQ1

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human GAD67
Gene ID 2571
Swiss Prot Q99259
Synonyms GAD; SCP; CPSQ1
Reactivity Human,Mouse,Rat
Application WB
Recommended dilution WB: 1:1000-1:5000
Calculated MW 67 kDa
Observed MW 67 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR12432
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

Western blot detection of GAD67 in Hela cell lysates using db11089(1:1000 diluted).

订购信息